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Clinically relevant SCFA deficiencies are observed in allergic rhinitis patients and infants predisposed to later asthma/wheezing development (Zhou et al., 2021), establishing these metabolites as critical mediators in allergic airway pathogenesis (Roduit et al., 2019)

These transcription factors increase the expression of Tyrosinase (TYR), a key enzyme involved in melanin synthesis, thereby stimulating melanin production (94, 95)

To speed up absorption drink on an empty stomach, and wait at least 15 minutes before eating

and trial design factors (endpoint selection, follow-up length)

This effect is achieved by increasing HO-1 activity and signaling to biliverdin reductase (BVR)