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reported increasing levels of 8-OH-dG in leukocyte DNA from healthy controls to undialyzed CKD patients, with the highest levels found in HD patients [51]

Trata-se de uma molcula naturalmente presente no plasma humano, saliva e urina, tambm liberada em processos de leso tecidual

S.BalakrishnanB.JyotiA.JanisseJ.et al (2012)

Hypertension contributes to atherosclerosis through endothelial dysfunction as well as a hyperactivation of the renin-angiotensin-aldosterone system (RAAS) and the sympathetic nervous system (SNS) (Zaheer et al., 2016)