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Pathophysiology Summary The common pathologic feature in PD and secondary parkinsonism is striatal dopamine deficiency

During pregnancy, its crucial to avoid unnecessary substances that could pose a risk to the baby, and currently there have been no well-controlled studies to establish that lipotropic injections are safe in pregnant women

10.1016/j.phymed.2025.156538 14 CaoF.XiangJ.WangY.ChenX.LuX.XuX.et al (2024)

Water Air Soil Pollut 235, 529 (2024)

Interestingly, after discontinuing Pycnogenol and placebo intake in the fifth cycle of the study, subjects of the Pycnogenol group reported a continuation of the trend, as their need for analgesics was even more reduced (50% compared to baseline), while women of the placebo group experienced a rapid return to analgesics

Griffiths RR, Johnson MW, Carducci MA, et al