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Basic and applied studies on -polylysine

Insulin sensitivity and lipid profile in prolactinoma patients before and after normalization of prolactin by dopamine agonist therapy

Therefore, although CRBN shows low affinity for dHTC1 and no detectable binding to ENL up to a concentration of 1 M, the stable, preformed ENL:( S )-dHTC1 complex can cooperatively engage CRBN with high apparent affinity to induce stereochemistry-dependent ENL degradation