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DMF diminishes ferroptosis stress in SCD mice Previously, we showed that DMF decreases the expression of plasma proinflammatory factors such as Il1a and Tnf in SCD mice 25 (Supplementary Fig

Liposomal encapsulation significantly enhanced transdermal delivery and barrier recovery, suggesting potential benefits in terms of stability, permeability, and immune modulation (Kim et al., 2015)

Click reaction mixture was prepared by sequential addition of 1 volume 10 mM azide-PEG3-biotin (Sigma, 762024), 2 volumes 50 mM CuSO 4 (Sigma, C8027), 2 volumes 50 mM TCEP (Sigma, 68957) and 1 volume 10 mM TBTA (Sigma, 678937)

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Despite its ubiquity, acetaminophen can cause significant hepatic injury at relatively low doses, and current therapy is limited and primarily supportive 12