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These individuals, born during the peri-surfactant era, demonstrated evidence of persistent airway oxidative stress, with increased 8-isoprostane when compared to term-born controls 45

Topical spironolactone is an important compounded option for female pattern hair loss, where oral finasteride and dutasteride are contraindicated

Mashiyama et al., 2014)

2022;20(4):e68295

In experimental models, inhalation of Cu nanoparticles in mice caused pulmonary toxicity and pulmonary fibrosis (Lai et al., 2018), and macrophages of patients exposed to asbestos had high levels of Cu and Zn-SOD/SOD1 and produced high levels of H 2 O 2 , whereas Cu, Zn-SOD/SOD1 deficient mice were protected from asbestos-induced lung damage and pulmonary fibrosis after exposure to asbestos in the trachea (He et al., 2011