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BMSC exosomes are internalized by damaged GCs, wherein the transferred miR-144-5p directly targets the tumor suppressor gene PTEN, which negatively regulates the PI3K/AKT signaling pathway (Huang et al

2011 Oct;49(8):755-9

The result is a renunciative therapeutic attitude of many urologists

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In the endosome it blocks entry of viral RNA (19) by not allowing the endosome pH to acidify, thereby preventing the acidic-pH-dependent conformational change required by the coronavirus spike protein to fuse with the endosome membrane (25, 26))