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Moreover, non-musculoskeletal and non-cutaneous manifestations may be associated with PsO and PsA, such as uveitis, inflammatory bowel disease, and other comorbidities, including obesity and metabolic syndrome, type 2 diabetes mellitus and cardiovascular disease 2

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The -phase half-life was calculated using the following formula: where t 1/2 is the -phase half-life, A e is the protein concentration at a specified post-injection time point, A 0 is the protein concentration on day 1, and t is the elapsed time

Many of these pain generators and sustaining factors cannot be seen on MRI

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