doi:10.1002/anie.201601585
192 In prostate cancer, HSP90 stabilizes the androgen receptor, enhancing its affinity for androgen and supporting tumor formation
Sanders TAB
The strongest correlations were seen with glutathione serum transferase (GST-Pi, hour 2 concentration, immediate function group 46 25 ng/mL versus 109 40 ng/mL in the fDGF group, n = 35, p = 6.1 10 6 , Fig
The core concept is that normal components of the tissue (or of the niche where the tumor grows) may provide, either occasionally or as part of a precise neoplastic strategy, a set of soluble factors that contribute to, or even determine, the growth of the tumor itself or facilitate immune evasion
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