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Drijard B, Hibi M, Wu IH, Barrett T, Su B, et al

Abstract The initial sensing of dietary methionine restriction (MR) occurs in the liver where it activates an integrated stress response (ISR) that quickly reduces methionine utilization

Nabwera HM, Espinoza JL, Worwui A, Betts M, Okoi C, Sesay AK, Bancroft R, Agbla SC, Jarju S, Bradbury RS, Colley M, Jallow AT, Liu J, Houpt ER, Prentice AM, Antonio M, Bernstein RM, Dupont CL, Kwambana-Adams BA

While GLP-1 receptor agonists are not associated with DKA, uncontrolled diabetes can lead to this emergency

Normal haematopoietic stem cells (HSCs) are characteristically quiescent and adapt their metabolic profiles at a low demand status to maintain their survival and produce multipotent progenitors in the bone marrow (BM) niche (7, 8)