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It is therefore assumed that transcription from gdhA P2 serves to enhance gdhA expression when the concentration of -ketoglutarate is low, as during invasive disease, both to enhance the activity of the TCA cycle in the catabolic reaction, and to provide L-glutamate for glutathione biosynthesis in the anabolic reaction

However, A recent systematic review indicated a favorable impact of AOX on pregnancy outcomes following ICSI (224)

Adapted from (O'Neill et al., 2016

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Among those compounds that had two aromatic rings along with the quinone structure, 1,4 naphthoquinone and lawsone showed slightly more inhibition