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A similar trend was observed with methoxy substitution ( 59 61 ) and dimethylaniline ( 62 64 ) with 4-position not being tolerated

In an ATP-dependent manner, GS adds glycine to -glutamylcysteine to form GSH

T1DM is recognized as an autoimmune disorder resulting from the pancreatic -cells destruction, eventually leading to impaired insulin secretion and hyperglycemia

Morrison and Preston, 2016

Furthermore, mitochondria perform various metabolic functions, such as redox buffering in the cytosol and calcium buffering, as well as play a critical role in biosynthesizing heme groups and membranes, the urea cycle, and metabolic adaptation [1, 19]