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At the molecular level, this occurs through the oxidation of a selenocysteine residue in GPx, followed by sequential interactions with GSH that regenerate the enzymes active form and release oxidized GSH Most GPx isoforms, including GPx1 to GPx3, function as tetramers composed of four identical subunits, each with a molecular weight of approximately 2223 kDa [105]

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Additionally, pathogens can trigger ARDS by interacting with receptors on alveolar epithelial cells

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