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When surgically removed, ductal adenocarcinomas average 3-5 cm in size and show invasion of surrounding tissue

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Guerreiro G, Faverzani J, Moura AP, Volfart V, Gome Dos Reis B, Sitta A, Gonzalez EA, de Lima Rosa G, Coitinho AS, Baldo G, Wajner M, Vargas CR (2021) Protective effects of L-carnitine on behavioral alterations and neuroinflammation in striatum of glutaryl-COA dehydrogenase deficient mice

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Acta Diabetologica (2003)

[70] Drug resistance [edit] Alteration of ARs may lead to treatment resistance (castration resistance) in prostate cancer as there may be missense mutations of the ligand binding domain, amplifications of the gene coding for this receptor or in its enhancer, mostly, suggesting the presence of different subclones with different genotypes of these receptors