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CSF rhinorrhea following medical treatment for prolactinoma: management and challenges

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CGM improves A1C and reduces hypoglycemia Insulin pump (CSII): Preferred for Type 1 patients on multiple daily injections failing glycemic targets

However, some protocols may explore alternate day dosing depending on the compound's half-life and the desired effect

Model Selection: In vitro: Primary hepatocytes, adipocytes, cells with high NNMT expression In vivo: DIO models, aging models, genetic obesity models Consider NNMT expression levels in chosen model 5

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