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When these junctions become damaged or weakened, the intestine becomes more permeable, leading to the condition known as leaky gut

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In contrast, DIO mice in both groups switched from WD to LD each had significantly increased Proteobacteria relative abundance (represented solely by the genus Parasutterella ) compared to both the WD and the LD controls, suggesting that Proteobacteria relative abundance may be largely influenced by stress or the differences in net energy expenditure (or associated body weight changes) caused by the diet switch

"The regime that we've been accustomed to for centuries is that we get the snowmelt, we capture it, then we use that storage to get us through the growing season," Stansbury said