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Statistical analysis was carried out with GraphPad Prism 8.0 or 9.0 software

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Change scores were created for all variables (i.e., post-diet minus pre-diet baseline scores) and Wilcoxon signed-rank tests or paired-sample t -tests were used for pre-to-post-diet comparisons for each measure, depending on passing the assumption of normality

The skin lightening soap category has benefited tremendously from clinical validation, with over 847 peer-reviewed studies published between 2018 and 2026 demonstrating efficacy and safety profiles for Kojic Acid, Alpha Arbutin, and Glutathione

While the exact cause of AD onset is still unclear, the prevailing hypothesis is that the increase in amyloid- (A) plaques and neurofibrillary tangles (NFTs) in the brain leads to synaptic dysfunction, and thus the onset of AD (Dias et al., 2014