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Feist Cardiovascular Research Fellowship to RP and the Endowed Chair in Diabetes to SKJ from the Center for Cardiovascular Diseases and Sciences (CCDS), LSUHSC, Shreveport, as well as grants to SKJ from the National Institutes of Health/National Center for Complementary and Integrative Health (RO1 AT007442, 2013-16)

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24 for the corresponding loop in MPGES1 (denoted C-loop) a direct amino acid interaction to the GSH from this loop was not observed in the MPGES1 X-ray structure (PDB ID: 4AL0) and can neither be found in the MPGES1 structure obtained by 2D-crystallography (PDB ID: 3DWW) 26

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