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Tier: animal models plus one controlled human topical trial

The tertiary structure of the peptide, the 3D shape that allows it to bind to GIP and GLP-1 receptors, starts to unfold

& Strmgaard, K

Lavoie H, Gagnon J, Therrien M (2020) ERK signalling: a master regulator of cell behaviour, life and fate

Gastrointestinal (celiac disease, IBD), endocrinal (hypothyroidism, hypoparathyroidism, type 1 diabetes mellitus), hematological (autoimmune hemolytic anemia), and dermatological (early onset acne, vitiligo, and psoriasis) are among the most prevalent CEAIDs in children with AIH [4, 9, 34,35,36,37,38]

It was worth mentioning that the catalytic activity of CDs increased significantly with the increase in irradiation time (Figure 4)