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Simultaneously, nutrients are oxidized in the cytosol and mitochondria to power ATP generation, reductive biosynthesis, and defense against reactive oxygen species

Although our study mainly focused on the protective role of MeCbl in inhibiting GSDME-mediated liver failure, it is important to note that GSDME is universally expressed in diverse other organs and may represent a key executor in mediating multiple pyroptotic organ damage

The Astragalus-Cordyceps combination effectively reverses intestinal microenvironmental dysbiosis in DN, significantly improving renal functional parameters with superior therapeutic efficacy compared to Astragalus monotherapy (Li J