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In vivo studies demonstrate that marijuana smoke exposure disrupts mitochondrial function and promotes oxidative stress, which can accelerate carcinogenic pathways (91)

But an audience can certainly decide whether a given performer knows, or does not know, his business - for this decision hinges upon whether the cigarettes seem to "materialize" in the air, or are rather obviously pulled from various parts of the performer's clothing

Even a small amount of alcohol can cause impairment

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