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Antioxidant and Anti-Inflammatory Research Laboratory studies investigate GHK-Cu in oxidative stress research: Antioxidant Enzyme Regulation: Research on superoxide dismutase (SOD), catalase, and glutathione peroxidase expression Reactive Oxygen Species (ROS) Modulation: Studies on oxidative stress reduction and cellular protection Anti-Inflammatory Pathways: Investigation of inflammatory cytokine modulation (IL-1, IL-6, TNF-) NF-B Pathway Research: Studies on inflammatory transcription factor regulation Oxidative Damage Protection: Research on lipid peroxidation, protein oxidation, and DNA damage prevention Experimental models include oxidative stress paradigms, inflammatory cell cultures, and models of inflammation-related tissue damage

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ONC201 induces p53-independent apoptosis and cell cycle arrest in hematological malignancies and leukemic stem/progenitor cells by inducing ER stress and mTOR inhibition

PRDX6-mediated pulmonary artery endothelial cell ferroptosis contributes to monocrotaline-induced pulmonary hypertension