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The Data are presented as mean values +/ SEM

In the presence of BSO, GA had no positive effect on the MMP (Fig

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Atomic absorption spectroscopy was utilized to measure the Cu concentration in the collected plasma sample using a validated Cu estimation methodology developed by the analytical lab

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This was associated with reduced expression of xCT (the catalytic subunit of Sxc ) and mGlu2 receptors [116], suggesting that a defective endogenous activation of mGlu2 receptors in the nucleus accumbens underlies the altered glutamate homeostasis that is ultimately responsible for the loss of control in drug-seeking behavior and relapse