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Senescence is also accompanied by disturbed organelle functions, such as distorted mitochondria, stressed endoplasmic reticulum, and defective lysosomes that are characterized by impaired degradative capability and highly expression of senescence-associated -galactosidase (-Gal) 4

Nitroglycerin and other nitrates may have theoretical interactions with glutathione that affect their cardiovascular effects

EpCAM signaling in oral cancer stem cells: implications for metastasis, tumorigenicity, and therapeutic strategies

doi: 10.1016/j.mce.2016.09.008, 20

Hence, a proper understanding of these factors helps establish optimal storage conditions for preserving the integrity of LNPs and their loads, ensuring that therapeutic efficacy is maintained throughout their shelf life

A Phase I and pharmacokinetic study of VNP40101M, a novel sulfonylhydrazine alkylating agent, in patients with refractory leukemia