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Metabolic reprogramming in cholangiocarcinoma

In contrast, IGFBP 5 tumor tissue levels have been found to be significantly associated with poor disease outcome and the addition of IGFBP 4 (measured as IGFBP 5 /IGFBP 4 ratio expression levels) further increased prognostic power [63]

Gclc fl/fl or Gclc fl/fl Mb1 Cre + mice) was used as input for the Compass algorithm 70,71

To assess synergistic effects between disulfiram and clinically used chemotherapeutics (daunorubicin, etoposide, cytarabine, mitoxantrone, and topotecan), we performed synergy assays with a panel of acute leukemia cell lines, including cell lines that are highly resistant to current chemotherapeutics (e.g., PER-485) [23]

Pulmonary symptoms and diagnoses are associated with HIV in the MACS and WIHS cohorts

Additionally, as an ex vivo model, a galactose-induced cataract model is known, in which the lens is cultured in a medium containing galactose 8