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10,11,15 Aging skin displays fragmentation of collagen and elastin fibers by the action of matrix metalloproteinase (MMPs), and increased mitochondrial oxidative stress results in deletions of mitochondrial DNA via the c-Jun/AP-1 pathway in dermal fibroblasts (Figure 1)

Mitochondrial respiratory efficiency is positively correlated with human sperm motility

The effects of alternate optimal solutions in constraint-based genome-scale metabolic models

The neurotoxicity of mercury Mercury has three forms, namely elemental mercury, inorganic mercury and organic mercury

As mentioned before, TYR converts tyrosine into DOPA, and subsequently DOPA to DQa distinctive orthoquinone that exhibits reactivity towards nucleophilic moieties, including thiol and amino groups

This refers to the situation where the chemical bonds (such as thioacetals, ester bonds, etc.) in the photolysis-triggered prodrug system are accidentally broken before reaching the target site (such as a tumor) due to interference from other biological factors in the body (such as enzymes, pH, reducing substances, etc.), resulting in premature release of the drug and causing off-target toxicity and reduced efficacy