The functional mechanism of E
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In certain embodiments, the amine-containing lipid has formula (IX): or a pharmaceutically acceptable salt, wherein: x is substituted or unsubstituted alkylene, substituted or unsubstituted alkenylene, substituted or unsubstituted alkynylene, substituted or unsubstituted heteroalkylene, substituted or unsubstituted heteroalkenylene, substituted or unsubstituted heteroalkynylene, substituted or unsubstituted carbocyclylene, substituted or unsubstituted heterocyclylene, substituted or unsubstituted arylene, substituted or unsubstituted heteroarylene, formula: X Independently hydrogen, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl, substituted or unsubstituted carbocyclyl, substituted or unsubstituted heterocyclyl, substituted or unsubstituted aryl, substituted or unsubstituted heteroaryl, nitrogen protecting group or formula: B1 And R in one case X Joined to form a substituted or unsubstituted heterocyclic ring or a substituted or unsubstituted heteroaryl ring, or R B2 And R in one case X Joined to form a substituted or unsubstituted heterocyclic ring or a substituted or unsubstituted heteroaryl ring, wherein: l for each case X Independently is a substituted or unsubstituted alkylene or substituted or unsubstituted heteroalkylene
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