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Targeting mitochondrial Complex I with metformin selectively inhibited growth and invasiveness in the docetaxel resistant cells, suggesting the resistant cells dependency on oxphos as a resistant adaptation (Pearce and Pearce, 2013)

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A trade-off threshold between number of input features and predictive power was assessed manually for each model

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Stabilizza i livelli di acetil-CoA e Coenzima A nei mitocondri, facendo uscire l'acetile residuo dai processi di ossidazione (responsabili della produzione di ATP), prevenendo cos l'effetto tossico di un eventuale accumulo

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