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All rats received Monastral blue (MB) (Sigma Company, USA) (1.0 ml/kg b.w., i.v.) 3 minutes before ethanol and the animals were sacrificed 1 minute after ethanol treatment

All libraries were pooled in equimolar amounts and sequenced on the Illumina NextSeq 500 at 50 bp forward read and 6 bp forward index read

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Exp Toxicol Pathol 44:169181 Davies KJ (1995) Oxidative stress: the paradox of aerobic life

Baoshan Liu, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Three P450 genetic polymorphisms have been particularly well characterized, affording some insight into possible underlying molecular mechanisms, and are clinically noteworthy, as they require therapeutic dosage adjustment