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Intravenously infusion of EUK-8 ameliorated acute lung injury in a highly stringent porcine endotoxin-induced model for the adult respiratory distress syndrome(Gonzalez et al., 1995b)

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PDE5 is abundantly expressed in the VSMCs of the pulmonary vasculature and is upregulated in PAH in the VSMCs, and in right ventricle (RV) cardiomyocytes.6366 The upregulation of PDE5 results in increased hydrolysis of cGMP

Serum lipoproteins and apolipoproteins in young male survivors of myocardial infarction

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(2017), male Sprague-Dawley rats were exposed to drinking-water containing aspartame at 68 mg/kg bw per day in week 1 and 1521 mg/kg bw per day in week 6