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The positive role of glutathione in preventing hypertension may also be explained by the observations that high glutathione levels prevent platelet-derived growth factor (PDGF)-mediated production of ROS by NADH/NADPH oxidase, which is considered to be the main source of vascular ROS (7), (22)

Contrary to L-lactate, D-lactate is still significantly synthesized in later phases, although at variable rates ( Figures 4D,E )

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It inhibits TGF-1-induced Smad3 phosphorylation, which is critical for the transcription of fibrotic genes [19]

MSCs derived from human gingiva also have immunomodulatory functions and ameliorate inflammation-related tissue destruction in mice with colitis