glutathione peroxidase in oxidative stress 4: a new player neurodegeneration? Trait: Oxidative Stress Risk (GPx-1)

BerteroTOldhamWMCottrillKAPisanoSVanderpoolRRYuQet alVascular stiffness mechanoactivates YAP/TAZ-dependent glutaminolysis to drive pulmonary hypertension

Kwon C-Y, Cho I-H, Park KS

103 As many as 93% of individuals treated with cisplatin chemotherapy may experience hearing impairment, which seriously affects the quality of life among cancer survivors

SAR treatment effectively mitigated reactive gliosis, significantly reducing both astroglial and microglial activation within these critical brain regions

CB-839 (N-(5-(4-(6-((2-(3-(Trifluoromethoxy)Phenyl)Acetyl)Amino)-3-Pyridazinyl)Butyl)-1,3,4-Thiadiazol-2-yl)-2-Pyridineacetamide) CB-839 is an oral GLS inhibitor developed on the basis of BPTES with a lower IC50 value (0.06 M) and stronger effect compared to BPTES (101)

Oral glutathione sold as a tablet or capsule in India falls under FSSAI's Health Supplements and Nutraceuticals Regulations, which require proper licensing, accurate labelling, and prohibit disease-cure claims