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The critical insight from clinical data is that relatively few participants discontinued tirzepatide due to side effects

8, 9, 10, 11 Oxidative stress occurs as the result of an accumulation of free radicals generated by normal metabolism and various environmental exposures to elicit cellular dysfunction

We took a closer look at this topic

DOI: 10.1155/2022/9966750 10

After 15 min, mitochondria were incubated with 1 mM NADH

In the course of the above phenomena, brain synapses and neurons are damaged, leading to a loss of integrity in neuronal systems, which dont operate sufficiently in isolation (Pistollato et al., 2016)