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Description

Increased ROS levels inhibit the KEAP1-mediated degradation of NRF2, which triggers a protective antioxidant defense

Burrough, Iowa State University, United States

These signals mutually interact to reshuffle the inflammatory microenvironment of autoimmune diseases

Furthermore, we highlight the pathways through which materials science, including exosomes, hydrogels, and nanomaterials, can alleviate SCI by modulating ROS production and clearance