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Engel B, Laschtowitz A, Janik MK, Junge N, Baumann U, Milkiewicz P, et al

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In many persistent cases, the problem is that the right combination of mechanisms was not treated togetherbut it should be

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Dysbiosis amplifies barrier dysfunction and immune activation, while inflammation further perturbs microbial composition and impairs epithelial repair, establishing a self-sustaining pathological cycle