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Vishnu et al., 2024

Arginine is broken down into urea and ornithine [219], which are precursors of the synthesis of putrescine, spermine, and spermidine [219]

Kim YR, et al

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Indeed, oxidative stress hampers chromatin reprogramming including DNA methylation, which has important consequences on the formation of the protamine shield protecting DNA from oxidative stress and thereby DNA damage