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Le Cu2+ libre est toxique (reactions de Fenton, radicaux hydroxyle), mais le complexe GHK-Cu est stable, diffusible et delivre le cuivre de maniere ciblee vers les metalloenzymes dependantes : lysyl oxydase (reticulation collagene/elastine), superoxyde dismutase Cu/Zn (SOD1, defense antioxydante), tyrosinase (melanogenese controlee), dopamine-beta-hydroxylase

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The gradient alloyed QDs high colloidal stability is demonstrated by their zeta potential values, which are lower than 30 mV

10.1177/0883073812448535 J

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