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For patients where the BPC-157 pathway is no longer accessible, the substitute strategy whether an alternative peptide, conventional pharmacologic therapy, or conservative management should be characterized in advance

For established acne scars, the peptide would need to be combined with treatments that create fresh wounds (microneedling, laser) to re-activate healing processes that BPC-157 could then support

The peptide activates the FAK-paxillin signaling pathway, which is essential for cell migration and tissue reorganization during repair processes

of this final rule with comment period for more details on this estimated burden calculation

2024 Apr 3;17(4):461

Differential expression analysis was performed using the DESeq2 package (version 1.42.1) in R 56