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Median lethal needle caliber in two models of experimental sepsis

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Orthotopically implantation in the posterior fossa of NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ (NOD scid gamma deficient, NSG) mice of the DAOY or D283-Med cells led to the generation of tumors

36, the dimers formed from two phenolic hydroxyl groups in compounds A, B, and C were present in very low amounts compared to C

Fer-1 has similar predicted lipophilicity, but much greater erastin-suppressing potency than two canonical lipophilic antioxidants (trolox and butylated hydroxyltoluene [BHT]), while being both considerably more lipophilic and more potent than two representative soluble antioxidants (Tiron, TEMPO) (FIGS

Interestingly, for genes that were down-regulated, 152 (64.7%) in day 7 and 433 (83.9%) genes in day 28 were exclusively down-regulated (Fig