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The underlying assumption is that depending on the nature of the in vitro manipulation, the embryo could be differentially impacted, leading to different phenotype outcomes in later life stages 4,5,11,12,13,14,15

The cost of discarding a partially degraded large vial often exceeds the negligible price difference of buying smaller units, making multiple small vials the more cost-effective choice for extended protocols

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Short-term tolvaptan increases water intake and effectively decreases urinary calcium oxalate, calcium phosphate and uric acid supersaturations

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Safety profiles vary significantly between individuals based on genetic, inflammatory, and metabolic factors