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Of note, authors reported interaction between ceramides and the PINK1 protein affecting mitochondria function and mitophagy

The best predictive accuracy for 5-year incident asthma exacerbations, including 21 sphingolipid:steroid ratios serum IgE level, and baseline variables (race, ICS medication), achieving an area under the curve (AUC) of 0.901 (Supplemental Data 6)

Moreover, it can inhibit the adhesion of leukocytes and platelets to the vessel walls [50, 51], contributing to preventing thrombus formation

The isozymes CYP 2 E 1 , CYP 1 A 2 , and CYP 3 A 4 contribute to alcohol oxidation in the liver