does melanotan work for vitiligo Full article: Sustained Repigmentation in and Leukodermas Using Melanocyte–Keratinocyte Transplantation: 7 Years of Data Clinuvel Completes Enrollment in Phase

Melanoma-in-situ (MIS) is a high risk lesion due to three primary reasons

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Apart from the beneficial effects and detrimental side effects of melanin production, melanocytes can also protect against microbial infections by acting as antigen-presenting cells producing cytokines, phagocytosing microorganisms, and degrading both phagocytosed bacteria and bacteria in the microenvironment by means of melanosomal lysosomal enzymes [4, 6, 7]

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Protection of the skin against solar damage, by sunburn and suntan either by natural sunlight, tanning beds, or the use of sunlamps, is necessary, especially if a positive family history is given