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Evaluation of fertilization and embryo production rates After IVF, the oocytes were fixed in 0.5% glutaraldehyde (v/v) for 15 min at room temperature and stored at 4 C until analysis

Arterioscler Thromb Vasc Biol 24(2):313319

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The CS/UC-MSC-EXOs transplantation considerably encouraged endometrial regeneration, collagen reconstruction, hormonal activity, and fertility restoration

In conclusion, immune-inflammatory interactions within the testicular-penile microenvironment are biologically plausible core pathophysiological mechanisms underlying varicocele-related spermatogenic impairment and the proposed association with erectile dysfunction, and the hypothesized systemic dissemination of inflammation forms a mechanistically supported pathological link between the two organs