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It was noted that the effects of UK-5099 treatment on GSH reduction and replication stress were less in 32D cells (Fig

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doi: 10.5414/CP203602 134

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Mechanistically, a role of intracellular calcium release and uncoupling of mitochondrial respiration in oleic acid-induced IL-1 secretion was revealed ( 4.4 Amino acid metabolism In macrophages, amino acid catabolism plays a crucial role in controlling multiple macrophage response pathways - including mTOR signaling and NO generation and immune characteristics (Kieler et al., 2021)

218 NF-B inhibitors can inhibit NF-B through different mechanisms, such as blocking the nuclear translocation of NF-B, inhibiting the activation of NF-B, and antagonizing the NF-B signaling pathway