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Other studies showed that the intravenous administration of high doses of either 500 or 750 mg/kg ALCAR to awake adult Fischer-344 rats significantly increased uptake and phosphorylation of [ 14 C]2-deoxy-D-glucose ( 14 C-DG) used to determine the cerebral regional metabolic rate of glucose (rCMRglc) [126]

3402-A ASK1/p38 AXIS INHIBITION BLOCKS THE RELEASE OF MITOCHONDRIAL DANGER SIGNALS FROM HEPATOCYTES AND SUPPRESSES PROGRESSION TO CIRRHOSIS AND LIVER CANCER Zhenwei Peng 1,2 , Guangyan Wei 1,2 , Pinzhu Huang 1 , Ping An 1 , Shuangshuang Zhao 1 , Yi Lin 1 , Li Tan 1 , Kahini Vaid 1 , Disha Skelton-Badlani 1 , Imad A

Compound Tongluo Decoction inhibits endoplasmic reticulum stress-induced ferroptosis and promoted angiogenesis by activating the Sonic Hedgehog pathway in cerebral infarction