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Description

These reactions can be life-threatening and require immediate medical attention

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In vitro, 5-Amino-1MQ at 30 M in 3T3-L1 adipocytes significantly reduced intracellular 1-MNA levels, confirming NNMT target engagement

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Since this heterozygous mutation in Insr alone was insufficient to induce defective glucose homeostasis, we challenged the mice with HFD

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