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The term acute refers to kidney dysfunction occurring within hours to days, while kidney injury implies a potentially reversible condition that, if not promptly addressed, may progress to acute kidney disease (AKD) and even chronic kidney disease (CKD) [3, 4]

References 1 AbalovichM.AminoN.BarbourL

Under the stimulation of cytokines secreted by mature DCs (mDCs), T cells and B cells polarized into inflammatory subsets

Wang Z, Pang S, Liu X, Dong Z, Tian Y, Ashrafizadeh M, Rabiee N, Ertas YN, Mao Y

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However, because AOD9604 is often selfadministered outside clinical settings, the safety margin can vary depending on sourcing, dosing accuracy, and overall protocol design