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Future Med Chem 4:15271531 Beysen C, Murphy EJ, Nagaraja H et al (2008) A pilot study of the effects of pioglitazone and rosiglitazone on de novo lipogenesis in type 2 diabetes

GHK-Cu is a complex of copper and glycyl-l-histidyl-l-lysine (GHK), a peptide present in human plasma, saliva, and urine that decreases in concentration as we age

However, another mechanism may be that the pentadecapeptide BPC 157 can directly protect against paracetamol induced brain damage

Because so much of GHK-Cus activity is copper-mediated, it is difficult in some experiments to separate specific tripeptide signaling from generic copper effects a point made concrete by the finding that the MMP-2 effect was reproduced by copper ions alone while the collagen-synthesis effect required the intact peptide

It's well studied for skin, but nobody has tested whether restoring GHK-Cu actually slows aging anywhere else

By enhancing melatonin production, Epithalon may indirectly support cellular repair and immune system activity