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Building on this mechanistic foundation, this article critically assesses the evolving therapeutic landscape

Aggregates of alpha-synuclein (syn) phosphorylated at serine 129 (PSER129) are hallmarks of synucleinopathies, which, for PD/DLB, are found predominantly in neurons, whereas in MSA, aggregates are primarily found in oligodendroglia

Moreover, some tumor cells that resist radiotherapy and chemotherapy can change to the secondary form of glioblastoma lesions and cause tumor recurrence