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For metabolic function specifically, adenosylcobalamin is the form most directly involved in mitochondrial fatty acid and amino acid processing

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Its lack of additives makes it a safe option for applications where preservatives could pose risks, such as in pediatric or neonatal care

This same commenter suggested that CMS should consider in the interim, implementing waivers for individual cases where an audio-only telecommunications evaluation of the patient is the only means that a patient can access services, or where there is an insufficient supply of OTP providers in the area to prescribe or dispense methadone